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案例:某虹膜炎患者,医生给予阿托品滴眼等治疗措施。用药后患者出现瞳孔扩大,视物不清,畏光,疑病情加重,第二天再次复诊。问 ①阿托品为什么会引起瞳孔扩大? ②患者是否一定是病情加重? I Receptors 1.Dentification Receptor a part of neuron or a specialized cell Sense organ Receptor + non-neural cells
2.Classifications
location:
exteroceptor interoceptor type of stimulus:
mechanoreceptor thermoreceptor nociceptor electromagnetic receptor chemoreceptor 3.Characteristics of receptor (1)differential sensitivity * adequate stimulus * sensory threshold (2)Transduction
*receptor potential *generator potential
Mechanism
Characteristics
(3)Encoding To transform the information from stimulus into a train of nerve impulses The quality (modality) of sensation specific part of the brain The quantity (intensity) of sensation Frequency of AP Number of activated receptor (4) Adaptation when a maintained stimulus of constant strength is applied to a receptor, the frequency of the AP in its sensory nerve declines ever time.
A maintained constant stimulus, the impulse frequency ↓ rapidly adapting receptor slowly adapting receptor
II eye 1. Anatomy
2. Optics of the eye (1) Refraction of light
(4) Visual acuity 人眼辨别物体微细结构的最大能力,即辨别两点空间最小距离的能力 为什么不能看清无限远的物体:太远光线太弱 太远在视网膜上成像太小 (5) Accommodation
parasympathetic nerve ②near point 眼能看清的最近距离 μ elasticity of the lens 8 years old 8.6 cm 20 years old 10.4cm 60 years old 83.3cm
(6) Near response ①accommodation ②Pupil contraction near reflex of pupil
③Convergence convergence reflex (7) Errors of refraction
*Emmetropia normal vision *Myopia Nearsightedness Characteristics: parallel light rays are focused in front of retina Causes too long eyeball Too much refractory power Correction concave lens *Hyperopia : Farsightedness Characteristics: parallel light rays are focused behind retina Cause too shoot eyeball too weak refractory power Correction convex lens *Astigmatism Characteristics light rays are refracted to different focus Cause the currature of refractive system are not uniform Correction cylindrical lens *presbuopia Characteristics near point ↑ Cause elasticity of the lens ↓ Correction conves lens (8) visual field (9) binocular vision and stereopsis
3. photoreceptor function of retina (1) structure of retina
(3) photochemical reaction of rhodopsin
(5) dark adaptation and light adaptation ①dark adaptation
②light adaptation *level of photochemical *pupilary light reflex sensitivity to light 500,000~1000,000 times ③night blindness vitamine A ↓ (6) color vision Trichromacy theory
*color blindness
III Ear External ear Ear Middle ear Inner ear cochlea
1. hearing threshold and fragnency range of hearing
*hearing threshold *frequency range of hearing
思考题
1.简述视近物时眼的调节过程 2.简述视锥细胞和视杆细胞的主要特点 3.简述常见屈光不正的种类、原因及矫正方法 4.简述耳是如何对声音进行初步分析的 参考文献 1. 姚泰.罗自强 生理学(七年制教材)人民卫生出版社2001 2. 姚泰 人体生理学(第3版)人民卫生出版社2001 3. Ganong WF. Review of medical physiology(20th) 1999 4. Guyton AC. Textbook of medical physiology(10th) 2000 |