药物动力学名词英中文对照表 |
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| absorption |
吸收 |
| albumin |
白蛋白 |
| allometric scaling |
类比法 |
| apparent volume of distribution |
表观分布容积 |
| biliary excretion |
胆汁排泄 |
| bioavailability |
生物利用度 |
| bioequivalence |
生物等效性 |
| biopharmaceutics |
生物药剂学 |
| blood brain-barrier |
血脑屏障 |
| blood-to-plasma concentration ratio |
血液-血浆浓度比 |
| central compartment |
中央室 |
| chiral drug |
手性药物 |
| clearance |
清除 |
| clearance rate |
清除率 |
| clinical pharmacokinetics |
临床药物动力学 |
| compartment |
房室，隔室 |
| competitive inhibition |
竞争性抑制 |
| conjugation |
结合 |
| dissolution |
溶解 |
| distribution |
分布 |
| dosage regimen |
给药方案 |
| drug interactions |
药物之间相互作用 |
| elimination |
消除 |
| elimination rate constant |
消除速率常数 |
| enantiomer |
对映体 |
| enteric-coated tablets |
肠溶片 |
| enterohepatic cycle |
肝肠循环 |
| enzyme |
酶 |
| equilibrium |
平衡 |
| excretion |
排泄 |
| extensive metabolizers |
快代谢型 |
| fecal excretion |
粪排泄 |
| first-pass effect |
首过效应，首关效应 |
| formulation |
剂型 |
| gastric emptying |
胃排空 |
| genetic polymorphism |
遗传多态性 |
| glomerular filtration rate |
肾小球滤过率 |
| half-life |
半衰期 |
| hepatic clearance |
肝清除率 |
| hepatocytes |
肝细胞 |
| high throughput screening |
高通量药物筛选 |
| hydrolysis |
水解 |
| in silico modeling (modelling) |
计算机模拟 |
| in vitro |
体外 |
| in vivo |
体内 |
| individualized therapy |
个体化给药，个体化治疗 |
| inducer |
诱导剂 |
| induction |
诱导 |
| infusion |
注射 |
| inhibitor |
抑制剂 |
| inhibition |
抑制 |
| interactions (see: drug interactions) |
相互作用 |
| intramuscular administration |
肌肉注射 |
| intestinal transit time |
肠道通过时间，经肠时间 |
| intravenous administration |
静脉注射 |
| intrinsic clearance |
内在清除率 |
| ionization |
离子化 |
| liver microsomes |
肝微粒体 |
| liver slices |
肝切片 |
| mechanism-based inhibition |
机理性抑制 |
| Michaelis constant |
米氏常数 |
| Michaelis-Menten equation |
米氏方程 |
| metabolism |
代谢 |
| noncompetitive inhibition |
非竞争性抑制 |
| oral administration |
口服给药 |
| oxidation |
氧化 |
| P-glycoprotein |
P-糖蛋白 |
| partition coefficint |
分配系数 |
| passive diffusion |
被动扩散 |
| perfusion rate |
灌注速率 |
| peripheral compartment |
外周室 |
| permeability |
通透性系数 |
| pharmacodynatics |
药效学 |
| pharmacogenetics |
遗传药理学 |
| pharmacogenomics |
|
| pharmacokinetics |
药物动力学 |
| physiology |
生理 |
| placental barrier |
胎盘屏障 |
| plasma |
血浆 |
| plasma protein binding |
血浆蛋白结合度 |
| polymorphism |
多态性 |
| poor metabolizers |
慢代谢型 |
| population pharmacokinetics, POPPK |
群体药物动力学 |
| racemate |
外消旋体 |
| recombinant enzymes |
重组酶 |
| reduction |
还原 |
| renal clearance |
肾清除率 |
| renal function |
肾功能 |
| sampling |
样品，样本 |
| scaling factor |
比放系数 |
| solubility |
溶解度 |
| steady state |
稳态 |
| substrate |
底物 |
| toxicology |
毒理学 |
| transporter |
载体 |
| uncompetitive inhibition |
反竞争性抑制 |
| variability (inter-individual variability) |
个体差异 |
| virtual screening |
虚拟筛选 |
| volume of distribution |
分布容积 |
| xenobiotics |
外源物 |
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